41 Comments
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jools's avatar

Over 15 yrs ago now I was on , Lamotrogeine and tegretol. I was medicated for 'idiopathic epilepsy " when looking back now I can see it was severe dorsal vagal collapse from the stress of my marriage ending and being the single mother of a baby with no money and a horrible family. Years later, I was put on Effexor and in another terrible relationship, I remember my partner crying because he'd hurt his ankle and I had no empathy at all.. none.. I told him to stop pretending to cry. This now makes total sense. I'm off them all now thank goodness and I have spent 15 yrs facing the mirror and now in my work as a psychotherapist , i help people wean from their medications having had the experience of being in their shoes. Once again I am appreciative of this article and your work.

Elizabeth D.'s avatar

I praise God for every practitioner who de-prescribes these medications. Bless you and the experience that yielded such wisdom.

PermieGeek's avatar

I hadn't heard of this effect from SSRIs before. Searched online and have been reading accounts for over an hour. It sure does explain a lot about what we are seeing happen in our culture. I'm going to try and spread this info within my sphere of influence.

PermieGeek's avatar

I just found out last night my sister is going on Abilify to counteract the emotional blunting she's experiencing. Yes she's on SSRIs and she won't listen to me but trusts her Dr.

Elizabeth D.'s avatar

Beg her with all the love in your heart to read Anatomy of an Epidemic. Get the book yourself and just read a couple of stories to her regarding the people the author highlights. DON’T give up on your sister. Please. Tear your clothes and throw ashes on your face. Make a spectacle of yourself to her. If that doesn’t work pay a stranger to get the info to her somehow. Whatever it takes. Never give up!

Enitharmon's avatar

She's on a road to hell. Hope you can make her see this somehow.

SteelJ's avatar

Just read this on Brownstone and had to flip over here to comment how great this piece is. Part of the problem is people want simple solutions for hard problems, so buy into the idea that drugs have these narrowly targeted effects that are well understood. It makes no sense to believe that. Nobody has a clue as to the ramifications of most any drug. If you're truly at the end of your rope, ready to kill yourself, sure, maybe it's worth trying something, anything, no matter how risky. Otherwise, life is supposed to be hard, as well as beautiful and rewarding. Trying to make it easy-breezy is exactly the wrong thing to do.

Mark Paine's avatar

Fucking brilliant, well done for this. I’ve been saying this for years and no one listens. I understand both as a RELATIONAL therapist and having used them. In fact the world of therapy seems to be disappearing into some sort cognitive conditioning and losing the plot when it comes to the very fabric of society, that good relationships are THE MOST IMPORTANT aspects of life and not something that seems to have become disposable or just traded in for another one and not necessarily another person.

Crixcyon's avatar

Excellent article. This is one facet of SSRI usage that I failed to see. Big pharma's dirty big secret is that it knows all drugs, vaccines and mRNA poisons steal your life from you. I am so pissed at what pain drugs have done to my wife that I want to tell all doctors of any kind to go to HELL. Most of them are pretty much useless as they cannot ever think beyond the AMA and big pharma BS.

Enitharmon's avatar

Inhibiting the capacity for love is perhaps their biggest effect… If you ask me.

jools's avatar

And since love is what will heal the world and given the anti human forces at play, I agree with you.

Nina Nelson's avatar

I was reading this and immediately thought of a podcast I heard the other day where they were talking about not practicing sorcery and the Greek word used for that in the Bible being pharmakeia. "It is related to the Greek word "pharmakon," which can mean "drug," "poison," or "spell". It's the root word for our modern term, pharmacy."

I believe God is bringing many things to light right now to remind us that marriage is, in fact, sacred, and that we need to fight to reclaim that. I did not come to this realization until after my divorce, of course. (A little back story if you want to read it: https://open.substack.com/pub/ninanelson/p/a-manifesto-of-love?r=1kxvwf&utm_campaign=post&utm_medium=web&showWelcomeOnShare=false)

Thank you for shedding light on this.

Marek Doyle's avatar

One of the most disappointing aspects of the current standard of care is the media's reflexive glossing over of these issues with the usual platitudes of 'the risks of side effects are outweighed by the proven benefits of SSRIs'...

If such a conversation is ever made in good faith, it would involve a discussion of this proof. According to Evidence-Based Medicine(TM), the best evidence comes from meta-analyses. One such study found that the NNT (Number Needed to Treat) for SSRIs in depression was 7-8, while another found it was 14-16. This means, even using the favourable figures, doctors prescribing SSRIs are generating huge changes in neurochemistry, despite them being mathematically guaranteed to fail 87% they are prescribed to.

Unfortunately, these trials are designed in a way that cannot possibly measure side-effects in an adequate manner.

(Links for these studies = https://pmc.ncbi.nlm.nih.gov/articles/PMC10576545/ and https://pmc.ncbi.nlm.nih.gov/articles/PMC4975858/).

Chris Marcon's avatar

It's the systematic chemical demolition of the human soul & the human experience by way of pharmakeia. I'm very gratefu that it alll is now finally becoming understood more broadly. Thanks . Important article . Another example is how modern street drugs cause total insanity and physiological deterioration within weeks . It's all connected .

Vanessa Maia's avatar

Excellent article!

People don't talk to each other anymore. Couples don't talk to each other anymore. I don't get why some people date or even get married if they don't even try hard to face their problems together. One flesh after you say "I do". Also, some people like to be labeled "sick". When I was younger, I worked with a lot of older people, and the thing they enjoyed talking about was "I am sick, I need this type of medication." Having diabetes was their mantra. Depression is the new diabetes.

jools's avatar

I think it’s a plea for attention.

It’s like a sort of unaware watered down munchausens. If you have a label of depression or ADHD or whatever it comes with a sort of expectation that “I’m different “ and a lot of what is sometimes just plain bad or entitled behaviour can be excused as “my depression, my ADHD”. In my experience, when people have little inner resource, the identity they take on as “patient” absolves self responsibility and looks outward for “cure”.

Phil Alethes's avatar

Thank you for this, Dr. McFillin. Sounds like you're doing good work. May your tribe increase.

In October 2023, a doctor wanted to put me on Lexapro, a popular SSRI "antidepressant". I prefer natural means of addressing health problems, and was not enthusiastic, but thought I should trust the guy, who I thought was going to be my "primary care provider" (PCP).

At 80, I'd pretty much avoided conventional medicine all my life, but after ~30 years of struggle with severe chronic health problems, both physical and psychological (including about a dozen years when I all wanted to do was die and get it over with) – mostly due, I now believe, to long-term effects of things that were done to me in infancy and childhood (e.g. the severe trauma of circumcision, for starters) – I was feeling desperate, so was coming rather new to the conventional medical world.

So I did start taking the medication, but after about a week I felt I didn't like what it was doing to me. I could feel that it might "help" with depression, as it seemed to establish a kind of mood floor below which I wouldn't sink. But it didn't make me happier. So I looked into it. And was horrified.

Basically, "Selective Serotonin Reuptake Inhibitors" raise the amount of serotonin in the brain, by blocking the brain's normal method of lowering an excess. But not only is serotonin not a "happiness hormone" – as SSRI marketers like to say – it's actually rather the opposite.

Similar to cortisol, its function is to prepare the nervous system and body to deal with a crisis situation, which it does by, among other things, turning off unnecessary functions like empathy and compassion, to ready you for violence if necessary. It's not an accident that nearly all school shooters turn out to be on SSRIs, and that many users commit suicide (two of the things they don't tell you). It puts you in a frame of mind where violence is likely to be the first option considered to deal with emotional distress.

This effect may also partially explain the attractiveness of these drugs to feminist-inclined women: it makes them more like men – or at least the simplistic notions that feminism promotes about men's character: able to make quick, hard decisions without being bothered by "female" considerations like compassion or reluctance to cause harm.

Fortunately, in the course of my research, I found my way to an online forum, Surviving Antidepressants (https://www.survivingantidepressants.org), a community of experienced volunteers providing peer support for tapering off all psychiatric drugs and their withdrawal syndromes. It's been online since 2011, and helped thousands of people. A search for "Lexapro" provided over 22,000 results. I didn't read them all :), but I did post a query, to which a helpful member replied:

"Since you were only on the Lexapro for 8 days, you can just stop cold turkey right now if you choose.  It takes about a month for the brain to adjust to the drug and become dependent on it."

"Become dependent on it?" See here for (some of) what they don't tell you: How psychiatric drugs remodel your brain (https://www.survivingantidepressants.org/forums/topic/1160-how-psychiatric-drugs-remodel-your-brain/?tab=comments#comment-10415).

I'd seen some articles around the Web about how to handle withdrawal, e.g. How to Stop Taking Lexapro and Cope with Withdrawal Symptoms (https://www.wikihow.com/Stop-Taking-Lexapro). It seemed difficult, but not impossible.

However, turned out there were lots of stories at Surviving from people who'd had a lot harder time than your doctor will tell you about (very few doctors know anything about SSRIs – beyond what they read in handouts from drug companies – but they prescribe them quite liberally). For instance, the member who'd responded to my query (username "getofflex") was on Lexapro for some seven years, then had to taper very slowly and carefully for FIVE YEARS to avoid ill effects.

Anyway, I stopped taking the drug, and after a sigh of relief, returned to the work with nutrition, supplementation, tonic herbal formulas (excellent results with Dragon Herbs: https://www.dragonherbs.com) and auto-psychotherapeutic work (therapist Pete Walker has been a great help: https://www.pete-walker.com; see his book "Complex PTSD: From Surviving to Thriving: A Guide and Map for Recovering from Childhood Trauma", which has nearly 10,000 5-star reviews at Amazon) that are more my cups of tea.

For women facing problems for which these horrific pharmaceuticals (from Greek "pharmakon" = poison, spell) are commonly prescribed, another supplier of excellent tonic herbs offers Athena Formula (https://lostempireherbs.com/product/athena), which looks worth a try.

I sent the doctor links to some of the information I'd found, and asked him some questions. AFAIK, he never looked at the links, nor did he answer my questions. He advised me to not do my own research, as there's a lot of misinformation on the Internet. (Gee, I didn't know that….) And told me I was not qualified to have an opinion, as I'm not a doctor. It is called playing Doctor without a degree or any medical experience.

Well, seems to me I'm the one going to have to live with what I put in my body, so why shouldn't I have an (informed) opinion? Also, the links I sent him were all from doctors – but apparently they weren't qualified to have opinions either.

Furthermore, he informed me that it is not necessary to taper off Lexapro. If and when you decide to stop the medicine you do not have to taper it off via a schedule. The medicine tapers itself when you stop it. Really? In hours of research, I'd never seen anybody else say this. I asked where he got this information; he didn't answer that question either.

Perhaps needless to say, I haven't been back to that doctor. Even though what first interested me about him was that he has been a public figure in opposition to circumcision. I guess spending 43 years playing God can have an effect on ones attitude.

Two years later, on my own amateur program, backed by a lifetime of interest in nutrition, herbal medicine, and work with my own mind in meditation and then with Pete Walker's methods (from his experience surviving a horrific childhood and then becoming a therapist to help others), I'm feeling a lot better. In a few weeks I'll be 82 years old, still struggling, but now feeling I might not die any moment, and in fact am growing steadily younger. The work is very slow, with frequent though now diminishing setbacks. But I haven't put any poisons in this body, nor had any of its parts excised, so the health I'm regaining I feel is real health and vitality.

God bless us every one.

Bernard Frassati's avatar

“God bless us every one.”

Indeed. Thank you for your excellent post. It feels like all the pieces are sliding into place when it comes to understanding what is happening to our society. SSRIs cause this (permanent?) emotion blunting. AI replaces our faculty for critical reasoning while lying to us. Social media is irrevocably broken. Porn is unrestricted to a frightening degree. Weed is now legal but the concentrations are through the roof. And then there’s screens.

I don’t know how we find our way out of this dark wilderness. It probably starts with saying “no” to as many “wonderful new solutions” as possible.

LD's avatar

I hear you Dr McFillin. I agree with you on every single point you make.

But I also have seen how human cultures have not thus far been capable of nuance. Long before SSRIs, there have been real abusive spouses. And now currently in real abusive marriage situations, real victims are also seeking help and being “helped” [not helped] by being drugged with SSRIs or other psychiatric psychotropic drugs—instead of helped to safely escape these situations. This is ALSO a travesty.

I want the fallacy of safe & effective to be exposed. But I would hate for after it is exposed and it’s been acknowledged by the medical establishment that these SSRIs are harmful to then be used as a blanket invalidation of real & true abusive situations.

Please also advocate that that does not happen??

Can we as human societies please learn to take things on case by case situations???

Ron's avatar

This sounds like my marriage. I used to think of us as the perfect couple and we would often get feedback from others about how great we were.

QUESTION: Is this reversible? I know she was on SSRI’s but I *think* she stopped. I don’t know, things are not better.

Her memory of the past is flooded with bad feelings. She says now she was suffering but kept it bottled up so 20 years and found herself and can let it out now.

It’s like I don’t know her anymore.

Zoe Mills's avatar

Have you joined the marriages destroyed by antidepressants ssris and snris group? If not I recommend you do, they can help answer your questions.

bloke's avatar

yep same here. Add a pile of other drugs for pain like cox inhibitors, statins and others to that mix and its pretty easy to see how it has to be them. Yep everything you said seems accurate but also a real war with sarcasm against males generally from what I'm hearing.

There would never be a recognition that the problem is the pills though so i can only see her getting worse.

Bernard Frassati's avatar

I am sorry this happened to you. I hope you find a way to stay together and you can get your “old wife” back.

Kate's avatar

I had a serious boyfriend at 17 so my parents put me on the birth control shot. The hormones made me a bit emotional (crazy) so I went to a psychiatrist and was put on Paxil. Please keep in mind none of the adults (that'd be the experts) made the connection between the birth control shot and my out of control emotional state. I was just poof! a crazy and depressed teenager, something the psychologist decided within ten minutes of meeting me with no conversation about the BC being a contributing factor.

I got off BC after two shots because my BF and I broke up 🤔 but stayed on the Paxil into my freshman year in college, when I slipped into some nihilistic catatonic state for about three days. I didn't know WTF had happened and called my parents in the middle of the night. The first thing they asked was if I was still on the Paxil. I said yes. My stepmother couldn't believe it and told me to wean me off them, which I did.

The crazier part, the prescribed dosage was so outrageous that my entire body shook when I began taking it. I had to cut it down from two pills a day to 1/2 pill a day and I never veered from this dose.

These drugs are TOXIC. The rollercoaster it put me on was crazy! And this article is correct, the drug is never even considered a contributing factor much less the sole factor to the rollercoaster while the individual is on it.

I was diagnosed with depressive manic disorder from a reaction and hormonal imbalance from a very strong birth control shot. AT SEVENTEEN! *I weighed 105 pounds.

Dr. Roger McFillin's avatar

This story is very common. Many do not make the connection.

ICI Grief (The Rebel's Hike)'s avatar

Well I guess this explains my sister's treatment of me after the death of my daughter in December of 2022. No real empathy at all. She's been on her happy pills for 30 plus years. Apparently destroyed.

Stephen Dedalus's avatar

“"Life's just much too hard today," I hear every mother say

The pursuit of happiness just seems a bore

And if you take more of those, you will get an overdose

No more running for the shelter of a mother's little helper

They just helped you on your way, through your busy dying day”

From *Mother’s Little Helper*

—The Rolling Stones